Effects of Age on Meiosis in Budding Yeast
نویسندگان
چکیده
منابع مشابه
Effects of age on meiosis in budding yeast.
In humans, the frequency with which meiotic chromosome mis-segregation occurs increases with age. Whether age-dependent meiotic defects occur in other organisms is unknown. Here, we examine the effects of replicative aging on meiosis in budding yeast. We find that aged mother cells show a decreased ability to initiate the meiotic program and fail to express the meiotic inducer IME1. The few age...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2009
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2009.05.013